Janssen put up $5 million to secure the licensing of Ionis’ antisense drug, IONIS-JBI2-2.5RX.. Cue Health has received $481 million from the U.S. Department of Defense to dramatically ramp up production of its hand-held diagnostic for COVID-19. © 2020 Questex LLC. But they also have a connection to Johnson & Johnson—they were awarded the Dr. Paul Janssen Award in 2014. Although these mutations were thought to be rare at the time, subsequent advances in DNA sequencing over the next decade would reveal that certain genetic alterations are linked to a variety of cancers, including bladder cancer. © 1985 - 2020 BioSpace.com. Ionis Pharmaceuticals ($IONS) has sold the rights to its early-stage GI autoimmune disease candidate IONIS-JBI1-2.5Rx to Janssen ($JNJ) as the company announces strong growth for Q2 and an uptick in R&D spend. The biotech also has R&D deals with Germany’s Bayer for IONIS-FXI in the prevention of thrombosis as well as AstraZeneca ($AZN) to develop antisense therapies for cardiovascular and metabolic diseases with the main focus on renal diseases, and other deals with Sanofi ($SNY) and GlaxoSmithKline ($GSK). “We learned during the course of our studies that bladder cancer patients with specific types of alterations responded well to the drug,” says Ademi Santiago-Walker links, Tag: Ionis licenses Through February of this year, Ionis had earned $47 million in fees and milestones, including $10 million paid by Janssen to license the first candidate under the collaboration. “This class of agents has a very narrow therapeutic index—too low or too high of a dose won’t be effective and safe,” says Kiran Patel A newly U.S. Food and Drug Administration (FDA)-approved treatment from Janssen, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, is helping to provide a promising option for some patients living with metastatic urothelial cancer, the most common type of bladder cancer.Spurred on by encouraging clinical trial results, the treatment received a special designation … Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., were just honored with the prestigious award for their work with gene-editing technology CRISPR. The company reiterated its use of partnerships--such as with Ionis--as a key driver for its sales and R&D productivity, calling its sales-to-research spend ratio one of the highest in the industry. Patrick Angibaud, Scientific Director and Fellow, Internal R&D Discovery, Janssen, Scientific Director and Fellow, Internal R&D Discovery, Janssen, co-lead the internal Janssen drug discovery program. You are now leaving jnj.com. Janssen Pharmaceuticals, Inc. manufactures, markets and/or distributes more than 51 drugs in the United States. Ademi Santiago-Walker, Associate Director, Translational Research and Biomarker Lead at Janssen, Associate Director, Translational Research and Biomarker Lead, Janssen. RELATED: Ionis licenses another antisense GI drug to Janssen. We are very pleased to have rapidly advanced this first drug candidate into development within a year and a half of initiating our collaboration with Janssen.
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