monoclonal antibody treatment omicron

The FDA limits the use of some monoclonal antibodies treatments, using remdesivir early in the course of illness, American Society of Health System Pharmacists. Doctors even began giving the drugs to people merely exposed to the coronavirus, as a way of preventing them from getting sick. endobj Also, a rapid rise in omicron infection rate across the country has affected transportation staff, which has contributed to these supply shortages. | Tudom ajnlani mindenkinek. The emergence of an Omicron sub-variant, BA.2, has made it even harder to get the right monoclonal antibodies to the right patients. Ezton is ksznm Tamsnak a gyorsasgt s megbzhatsgt! unlikely to reach the United States market anytime soon, will end its aggressive but contentious vaccine mandate. Among all the monoclonal antibodies tested, only Cv2.1169 and Cv2.3194cross-neutralized all variants of concern, including Omicron BA.1 and BA.2 subvariants. Todays authorization introduces the first treatment for COVID-19 that is in the form of a pill that is taken orally a major step forward in the fight against this global pandemic, Patrizia Cavazzoni, M.D., director of the FDAs Center for Drug Evaluation and Research, said in a news release. Monoclonal antibody drugs are a central part of the treatment tool kit against covid-19, proving remarkably effective at keeping people out of the hospital. Diploma, anyaknyvek s szakmai orvosi iratok szakszer hibtlan fordtsrt korrekt ron ezton is szeretnm kifejezni ksznetemet s ajnlom az rdeklknek, dv. rm az gyintzs ilyen krlmnyek kzt. Over the past year and a half, the drug sold in the U.S. under the brand Veklury had been used in hospitals to treat very sick patients with COVID-19. Ksznm! Nearly 68,000 doses of monoclonal antibodies were given nationwide last week, according to the Department of Health and Human Services. Rather than look in the blood of Covid survivors, researchers examined the blood of people who had survived the 2003 SARS epidemic, caused by a related coronavirus. For more information and all your COVID-19 coverage, go to theMayo Clinic News Networkandmayoclinic.org. PCR tests used by some healthcare institutions could detect one telltale mutation on Omicron, while others, like Houston Methodist Hospital in Texas, rolled out a test that could distinguish between strains as Omicron spread. She is a former staff writer for Forbes Magazine and U.S. News and World Report. Both Regeneron and Eli Lilly say they are developing monoclonal antibodies for Omicron, but it will be months before they are ready for use. x]Ks#7wD: M@='xl5"3_x@&waH& [Related: What we know about Omicrons latest variant]. Regeneron and Eli Lilly say theyre developing monoclonal antibodies that will work against Omicron, though they wont be available for months. In light of the most recent information and data available, today, the FDA revised the authorizations for two monoclonal antibody treatments bamlanivimab and etesevimab (administered together) and REGEN-COV (casirivimab and imdevimab) to limit their use to only when the patient is likely to have been infected with or exposed to a variant that is susceptible to these treatments. Omicron overpowers key COVID antibody treatments in early tests Nearly all of the monoclonal antibodies used to prevent severe disease fail to stand up to the As COVID-19 continues to evolve and mutate quickly, so do treatment options. %PDF-1.7 Anyone can read what you share. Registration on or use of this site constitutes acceptance of our Terms of Service. Fran Kritz is a freelance healthcare reporter with a focus on consumer health and health policy. The companies zeroed in on one or two that proved especially potent at stopping earlier versions of the coronavirus. h+y[eRJ&FtonBdoa}YUeS 8x?z{B]>. Some hospitals made them more accessible by setting up drive-through monoclonal antibody clinics. However, the emergence of the highly infectious Omicron variant rendered them largely ineffective. Remdesivir's role as a top COVID-19 treatment may be short-lived. WebThe Food and Drug Administration is no longer authorizing Bebtelovimab as a treatment for COVID-19 as of November 30, 2022, because it is not expected to neutralize Omicron sub-variants BQ.1 and BQ.1.1. Some nAbs, such as Sotrovimab, have exhibited varying levels of efficacy against different variants, while others, such as Bebtelovimab and Bamlanivimab Two antibody treatments approved earlier, made by Eli Lilly and Regeneron, worked against the Delta variant and other forms of COVID, but are not as effective against Omicron, The Times said. Csak ajnlani tudom! It takes more resources to administer than the antiviral pills and comes with substantial upfront costs, which stand in the way of widespread use. "As the omicron variant of COVID-19 continues its spread across the country, Mayo Clinic is refining its approach to effectively treat infected outpatients with monoclonal antibody and antiviral drug therapies. The one monoclonal antibody treatment that has performed well against Omicron in laboratory experiments is also the most recently authorized: sotrovimab, And it would be unlikely to change in new variants, the researchers reasoned. Health experts are supporting limited use of two monoclonal antibody treatments after reports that they were ineffective against Omicron. This is a dramatic change just in the last week or so, said Dr. Daniel Griffin, an infectious disease specialist at Columbia University in New York. But until production scales up, pills cant match the current volume of monoclonal antibody treatment, which means that for the moment, tough decisions remain about how to prioritize their use. "You don't want someone to get Dose 1 on a Friday, and wait 72 hours [to get the next dose]," says Wolfe. Nagyon meg vagyok elgedve a munkjval. The drugs are manufactured by Eli Lilly and Regeneron, respectively. A monoclonal antibody treatment site set up in Pembroke Pines, Fla., this summer. The current treatments include monoclonal antibodies (Sotrovimab) and antivirals (Paxlovid, Molnupiravir and While laboratory-based genomic sequencing tests can determine COVID-19 variants, those results are not consumer-facing. endobj Clszer a fordtnl rkrdezni vagy a A fordtson mindig szerepeljen a fordti zradk, a fordt pecstje, akrsa, a dtum, valamint legyen a PDF-hez csatolva a magyar Ksznjk a gyors s precz fordtst, mellyel maximlisan elgedettek vagyunk. The latest Updates and Resources on Novel Coronavirus (COVID-19). Philip Kiefer is a staff writer at Popular Science. Should the BA.2 subvariant grow in proportion in the U.S., this potential treatment may help ensure that we can continue to offer monoclonal antibody treatment that works against that strain of the virus.. The Eli Lilly and Regeneron monoclonal antibody treatments are directed against the spike protein of SARS-CoV-2, and Omicron has 32 mutations and a deletion Based on Centers for Disease Control and Prevention data, the omicron variant of SARS-CoV-2 is estimated to account for more than 99% of cases in the United States as of Jan. 15. That means a clinic could treat one patient with remdesivir or three patients with monoclonal antibodies in the same amount of time. Clinical trials showed that these antibodies were effective at preventing hospitalization if given to people early in the course of their illness. Treating patients with monoclonal antibodies is preferred because it's more efficient, says Wolfe. 2015. oktber 05. Drugmaker Gilead says remdesivir has proved effective at treating patients early in the course of the disease. Some U.S. health systems, including several New York City hospitals, had already stopped using the two treatments at the end of 2021. Dr. Bruce Muma, president of the Henry Ford Physician Network in Michigan, said health system administrators and state officials are bracing for a cutback on the Regeneron and Eli Lilly monoclonal antibodies, while anticipating only a meager supply of sotrovimab. FDA amended the emergency use authorizations, An infectious SARS-CoV-2 B.1.1.529 omicron virus escapes neutralization by several therapeutic monoclonal antibodies, CLIA SARS-CoV-2 variant testing frequently asked question. The single remaining monoclonal antibody therapy effective against the variant is now in short supply in the U.S., imperiling an option that doctors and hospitals have relied on. Maximlisan elgedett vagyok Tams gyors, megbzhat s precz munkjval. Fran Kritz is a freelance healthcare reporter with a focus on consumer health and health policy. Munkjval szemben minsgi kifogs mig nem volt. "Therapies for COVID-19 continue to evolve, and depending on the clinical condition of a patient and their risk factors, they may be eligible for treatment with monoclonal antibodies or antiviral drugs," says Dr. Raymund Razonable, a Mayo Clinic infectious diseases expert. The US Food and Drug Administration (FDA) even paused distribution of many monoclonal antibodies after Omicron became the dominant variant. Importantly, there are several other therapies Paxlovid, sotrovimab, Veklury (remdesivir), and molnupiravir that are expected to work against the omicron variant, and that are authorized or approved to treat patients with mild-to-moderate COVID-19 who are at high risk for progression to severe disease, including hospitalization or death. Most of the patients got Regenerons treatment, followed by Eli Lillys. In late December, as the omicron variant surged, the roster of early COVID-19 treatments was looking slim. Monoclonal antibodies for the treatment of COVID-19 tend to target the SARS-CoV-2 spike protein, which plays a vital role in mediating the entry of the virus into Copyright HungarianTranslation 2018 All rights reserved. Still, experts say, remdesivir has been a crucial option in this omicron surge, when virus mutations knocked out a few other treatment options. The FDA is advising against use of monoclonal antibodies from Eli Lilly and Regeneron to treat the Omicron COVID-19 variant because they are not very effective Gyors, nagyon segtksz, gyflkzpont! ____________________________________________. Omicron variant strains encode large numbers of changes in the spike protein compared to historical SARS-CoV-2 isolates. But because the supply of monoclonals is limited, he estimates the clinic infused around 130 people with remdesivir in January. While these therapies have been used to treat COVID-19 since late 2020, some treatments have become less effective or ineffective as COVID-19 mutates.The monoclonal antibody therapies authorized for emergency use by the Food and Drug Administration (FDA) to treat COVID-19 are: However, only sotrovimab may be effective against the newest variants of COVID-19, including omicron. Ksznm a szupergyors, profi fordtst s a folyamatos kommunikcit a rendelssel kapcsolatosan. Monoclonal antibodies were once considered the gold standard of COVID-19 treatment. Nzz krl s vedd fel velem a kapcsolatot, ha tudok valamiben segteni vagy, ha krdsed van. Paxlovid wont be immediately available to help people infected with Omicron because current supplies are limited. Although the treatments were widely used in California as late as last week, people opposed to vaccination requirements have especially relied upon the drugs. Administrators at NewYork-Presbyterian, N.Y.U. According to the National Institutes of Healths COVID-19 Treatment Guidelines Panel, the following treatments can be prescribed for patients with mild-to-moderate COVID-19 who are at risk of developing a severe case of the virus, including hospitalization or death: If youre living with a condition that puts you at high risk for a severe case of COVID-19, there are still several effective treatment options available if you get sick. The emergence of new variants of the SARS-CoV-2 virus has posed a significant challenge in developing broadly neutralizing antibodies (nAbs) with guaranteed therapeutic potential. Dr. Lindsay Petty, an infectious disease specialist at the University of Michigan School of Medicine, said that she and her colleagues were agonizing over when and if to switch from the abundant monoclonal antibodies to the scarcer sotrovimab. Ksznm szpen Tams. And, while other early treatments are in short supply, there's plenty of remdesivir to go around. 2015. jlius 14. Dec 23, 2021 -- Of the three monoclonal antibody treatments available in the United States to keep people infected with COVID-19 from becoming seriously ill, only And I think it makes sense.. A NAATI oldaln knnyen ellenrizheted A legjobb mg a megrendels eltt ellenrizned a fordt akkreditcijt, annak lejratt s irnyt. Maximlisan elgedettek vagyunk a szolgltatssal. Once we decide to change, we anticipate we will be running out of drug supply each week, she said. This extended half-life would bolster immunity for people who did not generate an adequate immune response to COVID-19 vaccination. Because data show these treatments are highly unlikely to be active against the omicron variant, which is circulating at a very high frequency throughout the United States, these treatments are not authorized for use in any U.S. states, territories, and jurisdictions at this time. Genomic sequencing, which public health researchers use to track COVID variants, takes at least a few days, but often stretches into a weekby which time, the window for antibody treatment has passed. AHA does not claim ownership of any content, including content incorporated by permission into AHA produced materials, created by any third party and cannot grant permission to use, distribute or otherwise reproduce such third party content. Plus it works against omicron while some other early treatment options do not. Monoclonal antibody therapies are laboratory-produced proteins created to bind to SARS-CoV2, the virus that causes COVID-19, and prevent it from attaching to <> stream That only leaves GlaxoSmithKlines That shortage has created problems at hospitals filling up with COVID patients. 2014. augusztus 27. The FDA left the door open for the return of the treatments if the prove effective against future variants. Hospitals, drug companies and Biden administration officials are racing to address one of the Omicron variants biggest threats: Two of the three monoclonal antibody treatments that doctors have depended on to keep Covid-19 patients from becoming seriously ill do not appear to thwart the latest version of the coronavirus. Therefore, its highly unlikely that COVID-19 patients seeking care in the U.S. at this time are infected with a variant other than omicron, and these treatments are not authorized to be used at this time. Ha akkreditlt NAATI fordtt keresel, j helyen jrsz. 2013. ta dolgozom akkreditlt NAATI (National Accreditation Authority for Translators and Interpreters) fordtknt s tolmcsknt. Ajnlom t mindenkinek, aki fordtt keres. Specialist 3rd Class Harley Sarmiento/U.S. This avoids exposing patients to side effects, such as injection site reactions or allergic reactions, which can be potentially serious, from specific treatment agents that are not expected to provide benefit to patients who have been infected with or exposed to the omicron variant. Its just $1 per month . A confluence of factors, including supply chain issues, and pauses and inconsistencies in distribution, have contributed to these treatment supply shortages. According to the Centers for Disease Control and Prevention, flu infection rates across the U.S. continue to bevery high. Pfizers treatment, known as Paxlovid, is especially promising, as it has been found to be highly effective and likely to work against Omicron. As we have throughout the COVID-19 pandemic, the U.S. Food and Drug Administration has used the best available science as the virus has evolved to make informed decisions with the health and safety of the American public in mind. Meglv tartalmak ellenrzse, lektorlsa, Weboldalak, zleti, jogi s pnzgyi tartalmak fordtsa. Mr az rajnlatbl kiderlt, hogy profival van dolgom. 2014. november 10. How Do Merck and Pfizers COVID Pills Compare? A hitelestett fordtst PDF-ben 24 rn bell, de akr mr a megrendels napjn e-mailben tovbbtom. The Omicron variant accounted for an estimated 73 percent of new cases in the United States last week, according to the Centers for Disease Control and Prevention. This last monoclonal antibody was bebtelovimab, delivered as a one-hour IV infusion. While the best ways to prevent the spread of COVID-19 are vaccinations and booster vaccinations, several authorized treatments and preventive drugs, including monoclonal antibody therapies, are used to treat patients at different stages.Monoclonal antibody therapies are laboratory-produced proteins created to bind to SARS-CoV2, the virus that causes COVID-19, and prevent it from attaching to human cells. 2014. oktber 11. On January 24, the FDA amended the emergency use authorizations (EUAs) for bamlanivimab and etesevimab (administered together) and REGEN-COV (casirivimab and imdevimab), limiting their use to only when the patient has been exposed to or infected with a COVID variant known to be treatable with these drugs. But the drug hasn't gotten much traction among health care providers because it takes significant time, staff and resources to give out. Langone and Mount Sinai hospitals said the hospitals will stop giving the Eli Lilly and Regeneron treatments, The Times reported, citing memos obtained and unnamed health system officials. Ensuring that healthcare providers on the frontlines have the best tools available to treat patients is a top priority for the agency. Two well used COVID-19 antibody treatments have been found to not work as effectively in diffusing the new omicron variant. At New York Community Hospital in Brooklyn, clinicians have been administering the Regeneron and Eli Lilly treatments to about 100 Covid patients daily. An infectious SARS-CoV-2 B.1.1.529 omicron virus escapes neutralization by several therapeutic monoclonal antibodies. WebMonoclonal antibodies are laboratory-made proteins that mimic the immune systems ability to fight off harmful pathogens such as viruses, like SARS-CoV-2. Fordti szolgltatst msnak is szvesen tudom ajnlani. Langone and Mount Sinai all said in recent days that they would stop giving patients the two most commonly used antibody treatments, made by Eli Lilly and Regeneron, according to memos obtained by The Times and officials at the health systems. When the coronavirus variants began emerging a year ago, researchers found that some had gained resistance to monoclonal antibodies. Initial clinical trials found that when given either Regeneron or Eli Lillys drug, an individual was 70 percent less likely to be hospitalized. It's the only early treatment available to children under 12. However, it is highly unlikely that anybody in the U.S. would be exposed to a variant other than Omicron at this time. Youre doing an awful lot of work to try to find the one or two Delta cases, says Long. Articles may contain affiliate links which enable us to share in the revenue of any purchases made. Kivl fordtsok, precz munka, minden hatrid pontosan betartva. WebMD does not provide medical advice, diagnosis or treatment. Dr. Griffin, who sees patients in New York City, said he expects difficult conversations now that major health systems have halted their use until the more effective treatment arrives. fordtsban s lektorlsban krjk mr vek ta Tams segtsgt. To accommodate the remdesivir treatments, the Duke clinic had to expand their hours from five days a week to seven. Treatment options are available across Mayo Clinic on an extremely limited basis. 2015. jlius 23. Ez a szolgltats t csillagos! The Food and Drug Administration today authorized emergency use of the But those most likely to be upset will be patients who didnt want to get vaccinated but thought, I can trust the monoclonals. 2015. szeptember 08. gyfeleim leginkbb szakmai tartalmak fordtst krtk tlem, gy tbbek kztt jogi, orvosi, mszaki, pnzgyi, kzgazdasgi tmj anyagokat fordtottam magyarrl angolra. Nat Med. Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years experience in consumer-oriented health and wellness content. Supplies of sotrovimab, the one remaining monoclonal antibody therapy still known to be effective, are scarce. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Therefore, we are pretty confident that they represent premium candidates for pre-exposure prophylaxis in immunocompromised patients.. If you have chosen to be less safe than you might have been, either because of your choice of vaccines or your choice of masking, its a riskier proposition than it would have been a couple weeks ago, Dr. Wachter said. Tams nagyon gyors szolgltatsval szinte nem lehet ms forditt egy napon emlteni. Those results put it on par with monoclonal antibodies and Paxlovid, a COVID-19 pill, which are the best available COVID treatments out there. For starters, remdesivir is a drug infusion that must be given intravenously, in a clinical setting. Monoclonal antibodies are lab-grown versions of antibodies that the immune system would make against COVID after an infection or vaccination. Now, with Omicron responsible for more than 99 percent of cases nationally, the FDA argues that it doesnt make sense to use the two ineffective monoclonal antibody treatments anywhere. In late December, as the omicron variant surged, the roster of early COVID-19 treatments was looking slim. While the FDAs language suggests that people with an earlier COVID-19 variant, like Delta, could use these monoclonal antibody treatments, theres really no way to know which variant youre infected with, especially at the start of a new wave. All rights reserved. Federal agencies now recommend remdesivir as one of four options for treating early COVID-19. Pfizer says preliminary lab studies also suggest the pill will hold up against the Omicron variant. Noncommercial use of original content on www.aha.org is granted to AHA Institutional Members, their employees and State, Regional and Metro Hospital Associations unless otherwise indicated. Information in this post was accurate at the time of its posting. To get monoclonal antibodies, a person needed to be diagnosed in time and able to get themselves to treatment. One aspect of our work highlights the role of IgA antibodies for a broad SARS-CoV-2 neutralization, Mouquet said. That might be a consideration to somebody who might be slapped with a co-pay," says Dr. Peter Chin-Hong, an infectious disease specialist at University of California, San Francisco. If you think of the virus as a set of Legos, each antibody is tuned to grab a specific brick. Not be expected to respond to COVID-19 vaccination or not be able to get vaccinated for COVID-19 for medical reasons. When the new variant was identified last month in southern Africa, researchers began laboratory studies testing monoclonal antibodies to see how well they worked against it. We cant even afford the slightest blip of a surge, and with Omicron that looks like whats coming, Dr. Muma said. Thats easier said than done. The NIH COVID-19 Treatment Guidelines Panel, an independent panel of national experts, recently recommended against the use of bamlanivimab and etesevimab (administered together) and REGEN-COV (casirivimab and imdevimab) because of markedly reduced activity against the omicron variant and because real-time testing to identify rare, non-omicron variants is not routinely available. However, the emergence of the highly infectious Omicron variant rendered them largely ineffective. The hospital ran out of its supply of the GSK-Vir treatment several weeks ago. There are several approved outpatient treatments for patients with mild to moderate symptoms of COVID-19 that have been shown to prevent progression to severe disease, hospitalization and/or death. You shouldnt really be using a therapy that doesnt work, says Feehan. Sotrovimab just happens to target spots of the virus that went unchanged. They reached out to those patients directly over the phone if they met certain [high risk] criteria. Nzz krl s vedd fel velem a kapcsolatot, ha tudok valamiben segteni vagy, ha krdsed van. Healthcare providers should consult the NIH panels COVID-19 treatment guidelines and assess whether these treatments are right for their patients. Monoclonal antibodies have become a mainstay of Covid treatment, shown to be highly effective in keeping high-risk patients from being hospitalized. For providers to get reimbursed, they "have to bill Medicare or a patient's insurance. The one monoclonal antibody treatment that has performed well against Omicron in laboratory experiments is also the most recently authorized: sotrovimab, made by GlaxoSmithKline and Vir Biotechnology and cleared in May. Monoclonal antibody therapy is a way of treating COVID-19 for people who have tested positive, have had mild symptoms for seven days or less, and are at high risk Sign up to receive Popular Science's emails and get the highlights. Even before Omicron, the monoclonal antibodies werent necessarily readily accessible to all patients, according to findings published by the CDC. Munkjt nagyra rtkelem s biztos vagyok benne, hogy a kvetkez alkalommal is hozz fordulok fordts gyben. Three are Omicron, for example, That left sotrovimab as the only FDA-approved monoclonal-antibody treatment option for infected people at high risk of developing severe COVID-19. For much of early 2021, supplies of the drug were limited, and they were given only to people at high risk of severe COVID. (The Department of Health and Human Services keeps a list of providers that can fill prescriptions for the medication.) Theyre given via an In other words, its use may be limited to times when monoclonals and pills are in short supply. FDA Scales Back Use of 2 Monoclonal Antibody Treatments for COVID-19. If I had a choice, I would give GSK, said Dr. Ralph Madeb, the hospitals co-chief medical officer. She is a former staff writer for Forbes Magazine and U.S. News and World Report. Megbzst mindig komolyan veszi, a munkt mindig idre elkszti. And like other infectious organisms, SARS-CoV-2 can mutate over time, resulting in certain treatments not working against certain variants such as omicron. Duke's infusion clinic, like many others, was set up to treat COVID-19 patients with monoclonal antibodies a treatment which takes a single infusion session lasting 1 to 2 hours, Wolfe explains. Therefore, the treatments arent to be used at all. Monoclonal antibodies are lab-grown versions of antibodies that the immune system would make against COVID after an infection or vaccination. Before sharing sensitive information, make sure you're on a federal government site. Correction: An earlier version of this story misstated the last name of Amy Feehan. Already in high demand even before Omicron arose, the supply of sotrovimab is very limited for now. In New York, hospital administrators at NewYork-Presbyterian, N.Y.U. The only antibody therapy that does appear to be effective against omicron is one made by British drugmaker GlaxoSmithKline, with U.S. partner Vir Biotechnology, called sotrovimab. For recent updates on COVID-19 treatments that are approved or authorized by the FDA, please visit the, An official website of the United States government, Director - Center for Drug Evaluation and Research, Recalls, Market Withdrawals and Safety Alerts, Coronavirus (COVID-19) Update: FDA Limits Use of Certain Monoclonal Antibodies to Treat COVID-19 Due to the Omicron Variant, estimated to account for more than 99% of cases in the United States. Flu cases and respiratory syncytial virus (RSV)rates are beginning todropin the U.S.; however, reported cases ofCOVID-19areincreasing. "Those therapies are just easier to administer, and they're going to end up being preferred," Ganio says. But the situation is likely to improve somewhat in the coming weeks. Monoclonal antibodies were once considered the gold standard of COVID-19 treatment. Vaccinated patients should still do well, he said. 4 0 obj |pnsuasu~~yO/6OO//od>V Y M'gl^~-.gLdU5eevq"d7P]v7|]?k%BSUFDD|W^z8iz?,v?y\jWyQ)+h 1 the current volume of monoclonal antibody treatment. For these reasons, health care providers consider remdesivir to be low on the list of treatment options available if necessary, but hard to implement. rajnlatltalnos rdekldsVisszajelzs, Szemlyes dokumentumok, okmnyok s okiratok hivatalos fordtsa magyarrl angolra, NAATI-akkreditlt tolmcs szolgltats hivatalos gyekhez. Over the next few months, the supply crunch on other highly effective COVID-19 treatments that can be taken at home as pills or given in a single infusion is expected to ease. He started as a freelancer for the science desk in 2021, and joined the team fully later that year. As a subscriber, you have 10 gift articles to give each month. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. The drug, called bebtelovimab from Eli Lilly, is a monoclonal therapy meant for COVID-19 patients as young as 12 who are at high risk for getting severely ill and who were recently infected, to keep them from getting even sicker and keep them out of the

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